Originally from Quebec City, Karine Boucher won First Prize and the Audience Choice Award in the Third Annual Ensemble Studio Competition. She received her master's degree and bachelor's degree in opera performance from the Québec Conservatory.

As a member of the Atelier lyrique de l'Opéra de Montréal, her credits include Miss Pinkerton in The Old Maid and the Thief and Micaëla in Carmen. Additional credits include Annina in La Traviata, Inez in Il Trovatore and Kätchen in Werther (Opéra de Montréal); and Damon in Acis and Galatea (Arte Music); Mimì in La Bohème (Jeunesses Musicales); and the title role in Rita (Highlands Opera Studio).

In 2014, she won the First Prize and the Audience Choice Award in the Canadian Opera Company Ensemble Studio Competition. In october 2014, she made her debut with Canadian Opera Company in the role of Kate Pinkerton from Madame Butterfly.

Upcoming roles with the COC include Helmwige in Die Walküre and Berta in The Barber of Seville (Ensemble Studio performance) as well as Donna Elvira (cover).